SCHEMBL6547576

SCHEMBL6547576

CC(=Cc1ccc(C)cc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
PTGS2 P35354 4/20 0.50
MAPT P10636 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
POLB P06746 1/20 0.50
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
NQO2 P16083 3/20 0.46
PTGS1 P23219 3/20 0.46
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.42
CYP1B1 Q16678 1/20 0.42
TSHR P16473 1/20 0.41
AKR1C3 P42330 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4602278 0.92 MAPT (0.59) ESR1ESR2PTGS2MAPTNPC1
SCHEMBL14199384 0.89 ESR1 (0.46) ESR1ESR2PTGS2MAPTNPC1
SCHEMBL18790028 0.89 ESR1 (0.68) ESR1ESR2PTGS2MAPTNPC1
SCHEMBL6546605 0.89 ESR1 (0.68) ESR1ESR2PTGS2MAPTNPC1
SCHEMBL1225178 0.87 ESR1 (0.58) ESR1ESR2PTGS2ALDH1A1NQO2
SCHEMBL726320 0.87 ESR1 (0.58) ESR1ESR2PTGS2ALDH1A1NQO2
SCHEMBL726321 0.87 ESR1 (0.58) ESR1ESR2PTGS2ALDH1A1NQO2
SCHEMBL9449494 0.84 ESR1 (0.57) ESR1ESR2PTGS2MAPTNPC1
SCHEMBL8712456 0.83 ESR1 (0.80) ESR1ESR2PTGS2RAB9AALDH1A1
SCHEMBL9806375 0.83 ESR1 (0.55) ESR1ESR2PTGS2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5488601-A Photoelectric sensor, information recording system, and information recording method DAI NIPPON PRINTING CO., LTD. (JP) 1996-01-30 US claimed
CN-106905471-A A kind of polyacrylate dispersion, its preparation method, coating and preparation method thereof 贵州黔兴建筑装饰材料有限责任公司 2017-06-30 CN disclosed
CN-106883714-A A kind of coating and preparation method thereof 贵州黔兴建筑装饰材料有限责任公司 2017-06-23 CN disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
EP-0622954-B1 Method and device for recording information DAINIPPON PRINTING CO LTD (JP) 2003-07-02 EP disclosed
EP-0690448-B1 Image reader system DAINIPPON PRINTING CO LTD (JP) 2001-09-19 EP disclosed
EP-0595255-B1 Photoelectric sensor, information recording system, and information recording method DAINIPPON PRINTING CO LTD (JP) 2001-03-28 EP disclosed
US-5932301-A COATING A MIXED SOLUTION OF A LIQUID CRYSTAL, A MULTIFUNCTIONAL ULTRAVIOLET CURING RESIN MATERIAL AND A FLUOROCARBON SURFACE-ACTIVE AGENT, AND THEN CURING THE COATING BY ULTRAVIOLET IRRADIATION DAI NIPPON PRINTING CO., LTD. (JP) 1999-08-03 US disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5793453-A Method and device for recording information, and method for measuring the transmittance of liquid crystals, which is applied to recording information DAI NIPPON PRINTING CO., LTD. (JP) 1998-08-11 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
US-5488601-A Photoelectric sensor, information recording system, and information recording method DAI NIPPON PRINTING CO., LTD. (JP) 1996-01-30 US disclosed
EP-0683187-A1 Hot melt adhesive composition for labels ENICHEM ELASTOMERI S.r.l. (IT) 1995-11-22 EP disclosed
EP-0622954-A2 Method and device for recording information, and method for measuring the transmittance of liquid crystals, which is applied to recording information DAI NIPPON PRINTING CO., LTD. (JP) 1994-11-02 EP disclosed
EP-0595255-A2 Photoelectric sensor, information recording system, and information recording method DAI NIPPON PRINTING CO., LTD. (JP) 1994-05-04 EP disclosed
US-4868225-A STERICALLY HINDERED META-PHENYLENEDIAMINE CHAIN EXTENDER FOR POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1989-09-19 US disclosed
US-4866208-A CURING AGENT FOR EPOXY RESINS; EXTENDERS FOR POLYUREA-URETHANE COPOLYMERS THE DOW CHEMICAL COMPANY (US) 1989-09-12 US disclosed
US-4792623-A CURING AGENT, EXTENDER THE DOW CHEMICAL COMPANY (US) 1988-12-20 US disclosed
EP-0082258-B1 SUBSTITUTED M-PHENYLENEDIAMINES THE DOW CHEMICAL COMPANY (US) 1986-02-19 EP disclosed
EP-0082258-A1 Substituted m-phenylenediamines THE DOW CHEMICAL COMPANY (US) 1983-06-29 EP disclosed