SCHEMBL4602278

SCHEMBL4602278

CC(=Cc1ccccc1)c1ccc(C)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
POLB P06746 1/20 0.59
ESR1 P03372 2/20 0.55
ESR2 Q92731 1/20 0.55
CYP1B1 Q16678 1/20 0.50
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
PTGS2 P35354 4/20 0.46
PTGS1 P23219 4/20 0.46
NQO2 P16083 3/20 0.46
ALDH1A1 P00352 2/20 0.45
TSHR P16473 1/20 0.45
AKR1C3 P42330 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ALOX5 P09917 1/20 0.43
NISCH Q9Y2I1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547576 0.92 ESR1 (0.55) MAPTNPC1RAB9APOLBESR1
SCHEMBL7803180 0.91 ESR1 (0.64) MAPTNPC1RAB9APOLBESR1
SCHEMBL18790028 0.89 ESR1 (0.68) MAPTNPC1RAB9APOLBESR1
SCHEMBL6546605 0.89 ESR1 (0.68) MAPTNPC1RAB9APOLBESR1
SCHEMBL1225178 0.87 ESR1 (0.58) ESR1ESR2PTGS2PTGS1NQO2
SCHEMBL726320 0.87 ESR1 (0.58) ESR1ESR2PTGS2PTGS1NQO2
SCHEMBL726321 0.87 ESR1 (0.58) ESR1ESR2PTGS2PTGS1NQO2
SCHEMBL25910341 0.86 PTGS1 (0.49) MAPTNPC1RAB9APOLBESR1
SCHEMBL8089190 0.83 ESR1 (0.80) MAPTESR1ESR2CYP1B1PTGS2
SCHEMBL8089192 0.83 ESR1 (0.80) MAPTESR1ESR2CYP1B1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458793-B1 BINDER RESIN FOR TONER AND ELECTROPHOTOGRAPHIC TONER FOR ELECTROSTATIC DEVELOPING USING SAID RESIN MITSUI CHEMICALS INC (JP) 2008-04-23 EP disclosed
EP-1641862-A1 SILYL ESTER COPOLYMER COMPOSITIONS Akzo Nobel Coatings International B.V. (NL) 2006-04-05 EP disclosed
US-20050227159-A1 Binder resin for toner and electrophotographic toner for electrostatic developing using said resin MITSUI CHEMICALS, INC. (JP) 2005-10-13 US disclosed
WO-2005005516-A1 SILYL ESTER COPOLYMER COMPOSITIONS AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2005-01-20 WO disclosed
US-20040038022-A1 Method of making a polypropylene fabric having high strain rate elongation and method of using the same MAUGANS REXFORD A (US) 2004-02-26 US disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0377507-B1 Aqueous dispersion and the preparation of foamed resins therefrom WITCO CORP (US) 1995-03-15 EP disclosed
EP-0377507-A2 Aqueous dispersion and the preparation of foamed resins therefrom WITCO CORPORATION (US) 1990-07-11 EP disclosed
US-4940732-A UNSATURATED POLYESTERS, DIACYL PEROXIDE, CARBONATE, GLYCEROL, MAGNESIUM ALUMINUM SILICATE, ALKALI METAL CARBOXYMETHYL CELLULOSE WITCO CORPORATION (US) 1990-07-10 US disclosed
US-4892854-A AROMATIC DIACYL PEROXIDE, ALKALI METAL CARBONATE OR BICARBONATE, MAGNESIUM ALUMINUM SILICATE, ALKALI METAL CARBOXYMETHYL CELLULOSE, GLYCEROL AND WATER WITCO CORPORATION (US) 1990-01-09 US disclosed