Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14207256 | 0.85 | PTGS1 (0.66) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL17531262 | 0.77 | HDAC6 (0.47) | CA12CA1CA2CA9HDAC6 | |
| Bicarbonate SCHEMBL25171118 | 0.77 | POLB (0.64) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7466601 | 0.76 | HDAC1 (0.46) | CA1CA2CA9HDAC6HDAC1 | |
| SCHEMBL28548456 | 0.76 | CA12 (0.59) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL2772977 | 0.76 | L3MBTL1 (0.59) | HDAC6HDAC1HDAC8ALDH1A1POLB | |
| SCHEMBL16038134 | 0.75 | HDAC1 (0.69) | CA12CA1CA2CA9HDAC1 | |
| SCHEMBL5767794 | 0.75 | CA12 (0.58) | CA12CA1CA2CA9HDAC6 | |
| SCHEMBL7217564 | 0.75 | CA1 (0.62) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL40711 | 0.75 | KMT2A (0.59) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361767-B2 | N-sulfonyldicarboximide containing tethering compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-04-22 | — | — | US | disclosed |