Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939709 | 0.86 | PTGS1 (0.64) | HDAC1HDAC7PTGS1PTGS2ENPP2 | |
| Hydrochloric Acid SCHEMBL7466609 | 0.84 | PTGS1 (0.62) | HDAC1HDAC7PTGS1PTGS2ENPP2 | |
| SCHEMBL16038134 | 0.81 | HDAC1 (0.69) | HDAC1HDAC7ENPP2MEN1KMT2A | |
| SCHEMBL12704514 | 0.79 | TP53 (0.53) | KMT2AMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL14207257 | 0.76 | CA12 (0.53) | HDAC1HDAC7PTGS1PTGS2MEN1 | |
| SCHEMBL8133573 | 0.76 | CASP3 (0.57) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL8133525 | 0.75 | ELANE (0.61) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL7460887 | 0.74 | PARP1 (0.49) | HPGDALDH1A1TDP1L3MBTL1CA1 | |
| SCHEMBL23872042 | 0.74 | MGLL (0.46) | MEN1KMT2ACA2FAAHMGLL | |
| SCHEMBL11724341 | 0.74 | ALDH1A1 (0.39) | HDAC1HDAC7PTGS1PTGS2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813546-B1 | PHOTOCHEMICALLY CROSS-LINKED POLYSACCHARIDE DERIVATIVES AS SUPPORTS FOR THE CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS | NOVARTIS AG (CH) | 2002-07-17 | — | — | EP | disclosed |
| US-6011149-A | ESTERIFICATION; CARBAMYLATION | NOVARTIS AG (CH) | 2000-01-04 | — | — | US | disclosed |
| EP-0813546-A1 | PHOTOCHEMICALLY CROSS-LINKED POLYSACCHARIDE DERIVATIVES AS SUPPORTS FOR THE CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS | Novartis AG (CH) | 1997-12-29 | — | — | EP | disclosed |
| WO-1996027615-A1 | PHOTOCHEMICALLY CROSS-LINKED POLYSACCHARIDE DERIVATIVES AS SUPPORTS FOR THE CHROMATOGRAPHIC SEPARATION OF ENANTIOMERS | NOVARTIS AG (CH) | 1996-09-12 | — | — | WO | disclosed |