Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.67 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.67 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452146 | 0.94 | FTO (0.70) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL1420636 | 0.93 | FTO (0.65) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL6662140 | 0.92 | FTO (0.74) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL1420534 | 0.86 | FTO (0.70) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL1908131 | 0.84 | HPGD (0.63) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL2332830 | 0.84 | FTO (0.67) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL3189664 | 0.84 | FTO (0.66) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL27956847 | 0.83 | FTO (0.65) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL3459139 | 0.83 | FTO (0.64) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL4743773 | 0.82 | FTO (0.60) | FTOMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013063405-A1 | METHODS OF TREATING GRAM-NEGATIVE MICROBIAL INFECTIONS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2013-05-02 | — | — | WO | disclosed |
| EP-2298327-A1 | ANTI-TUMOR AGENT | Toto Ltd. (JP) | 2011-03-23 | — | — | EP | disclosed |
| US-20090297620-A1 | Anti-Tumor Agent | TOTO LTD. (JP) | 2009-12-03 | — | — | US | disclosed |