Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14208261 | 0.83 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL4736451 | 0.83 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL4736465 | 0.81 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL4736459 | 0.81 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL4731523 | 0.79 | HSP90AA1 (0.40) | AMY1AHSP90AA1HSP90AB1HTR2AHTR2C | |
| SCHEMBL4786053 | 0.76 | L3MBTL1 (0.40) | L3MBTL1PKMTP53CYP1A2CYP2C9 | |
| SCHEMBL4786054 | 0.76 | L3MBTL1 (0.40) | L3MBTL1PKMTP53CYP1A2CYP2C9 | |
| SCHEMBL4735480 | 0.74 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL4735484 | 0.74 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL14207901 | 0.73 | L3MBTL1 (0.40) | L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059368-A2 | FUSED 2-AMINO PYRIMIDINE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | PFIZER PRODUCTS INC. (US) | 2008-05-22 | — | — | WO | disclosed |