Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14208261 | 1.00 | L3MBTL1 (0.33) | L3MBTL1GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL14208995 | 0.83 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL4736465 | 0.83 | L3MBTL1 (0.33) | L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL4736459 | 0.83 | L3MBTL1 (0.33) | L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL4735575 | 0.79 | GAA (0.39) | GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL4736448 | 0.77 | GAA (0.32) | GAAKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL14207901 | 0.72 | L3MBTL1 (0.40) | L3MBTL1GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4732637 | 0.72 | L3MBTL1 (0.40) | L3MBTL1GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4732639 | 0.72 | L3MBTL1 (0.40) | L3MBTL1GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL4735480 | 0.72 | L3MBTL1 (0.32) | L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059368-A2 | FUSED 2-AMINO PYRIMIDINE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | PFIZER PRODUCTS INC. (US) | 2008-05-22 | — | — | WO | disclosed |