Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 2/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433060 | 0.75 | DGAT1 (0.45) | POLBMEN1KMT2AMAPTCRHBP | |
| SCHEMBL2433058 | 0.75 | DGAT1 (0.45) | POLBMEN1KMT2AMAPTCRHBP | |
| SCHEMBL12328850 | 0.75 | NFKB1 (0.43) | MEN1KMT2AMAPTPTPN1PTPRA | |
| SCHEMBL612106 | 0.75 | PTPN1 (0.48) | POLBMEN1KMT2AMAPTCRHBP | |
| SCHEMBL14048862 | 0.74 | POLB (0.59) | POLBMEN1KMT2AMAPTCRHBP | |
| SCHEMBL8239558 | 0.73 | PTPN1 (0.62) | POLBMEN1KMT2AMAPTCRHBP | |
| SCHEMBL2432206 | 0.71 | DGAT1 (0.42) | POLBMAPTABL1DGAT1KDM4E | |
| SCHEMBL2432209 | 0.71 | DGAT1 (0.42) | POLBMAPTABL1DGAT1KDM4E | |
| SCHEMBL29936834 | 0.70 | MEN1 (0.57) | POLBMEN1KMT2AABL1KDM4E | |
| SCHEMBL2874727 | 0.68 | IKBKB (0.67) | POLBMEN1KMT2AMAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059042-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |