Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28214834 | 0.94 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2ATDP1THRB | |
| SCHEMBL18556218 | 0.85 | ALDH1A1 (0.41) | L3MBTL1MEN1KMT2ATDP1THRB | |
| SCHEMBL4788827 | 0.80 | CA12 (0.45) | L3MBTL1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL31258481 | 0.80 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL2350666 | 0.76 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2ATDP1THRB | |
| SCHEMBL22031687 | 0.76 | ALDH1A1 (0.38) | L3MBTL1MEN1KMT2ATDP1THRB | |
| SCHEMBL3943182 | 0.76 | MMP1 (0.39) | L3MBTL1MEN1KMT2ATHRBATM | |
| SCHEMBL31285979 | 0.75 | EPHX1 (0.48) | L3MBTL1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL29141676 | 0.74 | ALDH1A1 (0.35) | L3MBTL1THRBATMALDH1A1POLB | |
| SCHEMBL3399580 | 0.74 | ALDH1A1 (0.45) | L3MBTL1MEN1KMT2ATHRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297114-A2 | HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009154300-A2 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-23 | — | — | WO | disclosed |