Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694282 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL11868886 | 0.81 | KDM4E (0.43) | ALDH1A1MAPTHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11806010 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL8976843 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL32675956 | 0.77 | MAPT (0.53) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL11872002 | 0.77 | MAPT (0.33) | ALDH1A1MAPTHTTHPGDL3MBTL1 | |
| SCHEMBL6374912 | 0.74 | F2 (0.37) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL11803743 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL13316488 | 0.72 | SMN1; SMN2 (0.55) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL11807557 | 0.72 | ALDH1A1 (0.40) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329390-B2 | Detection of transmembrane potentials using N,N,N′-trialkyl thiobarbituric acid-derived polymethine oxonols | ANASPEC INCORPORATED (US) | 2012-12-11 | — | — | US | disclosed |
| US-8329390-B2 | Detection of transmembrane potentials using N,N,N′-trialkyl thiobarbituric acid-derived polymethine oxonols | ANASPEC INCORPORATED (US) | 2012-12-11 | — | — | US | disclosed |