SCHEMBL8976843

SCHEMBL8976843

COCCN1C(=O)CC(=O)N(CCOC)C1=S

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.41
MAPT P10636 5/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
LMNA P02545 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
BMPR1B O00238 1/20 0.33
BMPR1A P36894 1/20 0.33
TGFBR1 P36897 1/20 0.33
ACVRL1 P37023 1/20 0.33
ACVR1 Q04771 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4923748 0.83 MAPT (0.44) ALDH1A1MAPTSMN1; SMN2HPGDHTT
SCHEMBL14211413 0.80 ALDH1A1 (0.49) ALDH1A1MAPTSMN1; SMN2HPGDHTT
SCHEMBL11807557 0.78 ALDH1A1 (0.40) ALDH1A1MAPTSMN1; SMN2HPGDHTT
SCHEMBL6180533 0.77 MAPT (0.42) ALDH1A1MAPTSMN1; SMN2HPGDHTT
SCHEMBL11803961 0.77 F2 (0.43) ALDH1A1MAPTSMN1; SMN2HPGDHTT
SCHEMBL6162730 0.77 MAPT (0.35) ALDH1A1MAPTSMN1; SMN2HPGDHTT
SCHEMBL3629805 0.74 HTT (0.50) ALDH1A1MAPTSMN1; SMN2HPGDHTT
SCHEMBL145408 0.73 KDM4E (0.46) ALDH1A1MAPTSMN1; SMN2HTTKMT2A
SCHEMBL7737597 0.73 MAPT (0.50) ALDH1A1MAPTSMN1; SMN2HPGDHTT
SCHEMBL24683243 0.72 KMT2A (0.35) ALDH1A1MAPTHPGDHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5587279-A HIGH CONCENTRATION OF SILVER CHLORIDE GRAINS FUJI PHOTO FILM CO., LTD. (JP) 1996-12-24 US disclosed
EP-0384633-B1 Radiographic elements with selected speed relationships EASTMAN KODAK CO (US) 1996-04-24 EP disclosed
EP-0313474-B1 AN OPTICAL ARTICLE EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
EP-0313475-B1 AN OPTICAL ARTICLE CONTAINING A TRANSMISSION MEDIUM EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
EP-0313476-B1 AN OPTICAL ARTICLE CONTAINING A POLYMERIC MATRIX EXHIBITING A HIGH LEVEL OF SECOND ORDER POLARIZATION SUSCEPTIBILITY EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
EP-0341566-B1 DYE SENSITIZED PHOTOGRAPHIC IMAGING SYSTEMS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-23 EP disclosed
EP-0281381-B1 ELECTROLUMINESCENT DEVICE WITH MODIFIED THIN FILM LUMINESCENT ZONE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-07-15 EP disclosed
US-5021327-A Medical diagnosis EASTMAN KODAK COMPANY (US) 1991-06-04 US disclosed
US-4997750-A Reducing crossover in double coated x-ray film EASTMAN KODAK COMPANY (US) 1991-03-05 US disclosed
US-4973694-A FLUORESCENT DYES, FREE RADICAL POLYMERIZATION INITIATORS EASTMAN KODAK COMPANY (US) 1990-11-27 US disclosed
US-4743531-A PHOTORESISTS EASTMAN KODAK COMPANY (US) 1988-05-10 US disclosed
US-4743529-A PRINTED CIRCUITS EASTMAN KODAK COMPANY (US) 1988-05-10 US disclosed
US-4713321-A SENSITIZING DYES, OXIDIZERS SUCH AS PEROXIDES FUJI PHOTO FILM CO., LTD. (JP) 1987-12-15 US disclosed
EP-0111919-B1 MULTICOLOR PHOTOGRAPHIC ELEMENTS CONTAINING SILVER IODIDE GRAINS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-04-29 EP disclosed
EP-0185100-A1 PROCESS FOR PREPARING SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1986-06-25 EP disclosed
US-4520098-A CONTAINING FINE IODIDE SILVER HALIDE PARTICLES IN CONCENTRATION CAPABLE OF BEING DISSOLVED OUT EASTMAN KODAK COMPANY (US) 1985-05-28 US disclosed
US-4490458-A Multicolor photographic elements containing silver iodide grains EASTMAN KODAK COMPANY (US) 1984-12-25 US disclosed
US-4459353-A Gamma phase silver iodide emulsions, photographic elements containing these emulsions, and processes for their use EASTMAN KODAK COMPANY (US) 1984-07-10 US disclosed
EP-0111919-A2 Multicolor photographic elements containing silver iodide grains EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-06-27 EP disclosed
US-4439520-A Sensitized high aspect ratio silver halide emulsions and photographic elements EASTMAN KODAK COMPANY (US) 1984-03-27 US disclosed