Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.64 |
| ▸ | IDE | P14735 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | BAG3 | O95817 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421182 | 1.00 | MEN1 (0.71) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL1421179 | 1.00 | MEN1 (0.71) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL1421695 | 0.90 | MEN1 (0.71) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL1421701 | 0.90 | MEN1 (0.71) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL1421699 | 0.90 | MEN1 (0.71) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL1421331 | 0.84 | MEN1 (0.64) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL1421469 | 0.84 | MEN1 (0.64) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL18103076 | 0.82 | MEN1 (0.68) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL20005793 | 0.82 | MEN1 (0.68) | MEN1KMT2AMAPTMCL1IDE | |
| SCHEMBL1641528 | 0.81 | MEN1 (0.84) | MEN1KMT2AMAPTMCL1IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2011-04-28 | — | — | US | claimed |
| EP-2296476-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | Microbiotix, Inc. (US) | 2011-03-23 | — | — | EP | claimed |
| WO-2009142720-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2009-11-26 | — | — | WO | claimed |
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| EP-2296476-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | Microbiotix, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009142720-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | BLVRB, TFPI, FOSB | MEN1 4836/4885KMT2A 3896/4885MAPT 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.