Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | CDH1 | P12830 | 1/20 | 0.54 |
| ▸ | APC | P25054 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691149 | 0.88 | KDM4E (0.62) | KDM4EL3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL14416952 | 0.87 | KDM4E (0.79) | KDM4EL3MBTL1LMNAGAACDH1 | |
| SCHEMBL21942172 | 0.86 | KDM4E (1.00) | KDM4EL3MBTL1LMNAGAACDH1 | |
| SCHEMBL30934474 | 0.86 | KDM4E (1.00) | KDM4EL3MBTL1LMNAGAACDH1 | |
| SCHEMBL17656950 | 0.86 | KDM4E (0.57) | KDM4EL3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL14211970 | 0.84 | KDM4E (0.56) | KDM4EL3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL14211960 | 0.84 | KDM4E (0.59) | KDM4EL3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL23024890 | 0.82 | KDM4E (0.74) | KDM4EL3MBTL1LMNAGAASMN1; SMN2 | |
| SCHEMBL6262638 | 0.82 | KDM4E (0.71) | KDM4EL3MBTL1LMNAGAACDH1 | |
| SCHEMBL8016751 | 0.81 | L3MBTL1 (0.91) | KDM4EL3MBTL1LMNAGAACDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355340-B2 | Quinoxaline derivatives, organic semiconductor device and electroluminescent device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2008-04-08 | — | — | US | disclosed |
| US-7355340-B2 | Quinoxaline derivatives, organic semiconductor device and electroluminescent device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2008-04-08 | — | — | US | disclosed |