Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14211892 | 0.93 | CNR1 (0.91) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14181075 | 0.92 | CNR1 (0.80) | CNR1CYP2C9CYP2C19CYP3A4NPBWR1 | |
| SCHEMBL14181110 | 0.92 | CNR1 (0.80) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14212432 | 0.92 | CNR1 (0.80) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14211075 | 0.91 | CNR1 (0.76) | CNR1CYP2C9CYP2C19CYP3A4NPBWR1 | |
| SCHEMBL14181113 | 0.91 | CNR1 (0.76) | CNR1CYP2C9CYP2C19CYP3A4NPBWR1 | |
| SCHEMBL14212433 | 0.91 | CNR1 (0.84) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14211170 | 0.90 | CNR1 (0.86) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14181115 | 0.90 | CNR1 (0.75) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14211055 | 0.90 | CNR1 (0.75) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| EP-1697370-B1 | AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2007-04-25 | — | — | EP | disclosed |