SCHEMBL14212752

SCHEMBL14212752

CC/C=c1/cc2c(cc1C)=C(c1ccccc1C(=O)NCC(=O)N1CCCC1C(=O)N1CCCC1C(=O)N1CCCC1C(=O)O)c1cc(C)c(NCC)cc1O2

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 0.35
FAP Q12884 11/20 0.33
PREP P48147 1/20 0.32
ITGB1 P05556 2/20 0.32
ITGA4 P13612 2/20 0.32
ITGB3 P05106 1/20 0.32
ITGAV P06756 1/20 0.32
ITGA5 P08648 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
PSMD14 O00487 1/20 0.32
P2RY12 Q9H244 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14212747 0.95 FAP (0.33) FAPPREP
SCHEMBL16489111 0.78 MYC (0.34) MEN1KMT2A
SCHEMBL14681719 0.76 LMNA (0.35) MEN1KMT2A
SCHEMBL15290195 0.74 FAP (0.34) ACEFAPPREP
SCHEMBL25207239 0.72 MYC (0.35) MEN1KMT2A
SCHEMBL15290194 0.69 FAP (0.34) FAPPREP
SCHEMBL14870371 0.66 GAA (0.34) MEN1KMT2A
SCHEMBL12302213 0.64 TSHR (0.36) MEN1KMT2A
SCHEMBL25266487 0.64 MYC (0.34) MEN1KMT2A
SCHEMBL17399551 0.63 HTT (0.32) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120309045-A1 Composite Probes and Use Thereof in Super Resolution Methods THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2012-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309045-A1 Composite Probes and Use Thereof in Super Resolution Methods BLM, SFPQ, RAD51 ACE 4373/4885FAP 1455/4885PREP 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.