Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.67 |
| ▸ | HPGDS | O60760 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715572 | 0.90 | ECE1 (0.66) | ECE1HPGDSALOX15KDM4EMEN1 | |
| SCHEMBL29599837 | 0.90 | ALOX15 (0.71) | ECE1ALOX15KDM4EMEN1LMNA | |
| SCHEMBL3831270 | 0.90 | ALOX15 (0.71) | ECE1ALOX15KDM4EMEN1LMNA | |
| SCHEMBL3829865 | 0.90 | ALOX15 (0.71) | ECE1ALOX15KDM4EMEN1LMNA | |
| SCHEMBL29865999 | 0.90 | ALOX15 (0.71) | ECE1ALOX15KDM4EMEN1LMNA | |
| SCHEMBL5374217 | 0.90 | ALOX15 (0.71) | ECE1ALOX15KDM4EMEN1LMNA | |
| Acetyltryptophanamide SCHEMBL22850012 | 0.89 | ECE1 (0.68) | ECE1HPGDSALOX15KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL27511139 | 0.89 | ALOX15 (0.70) | ECE1ALOX15KDM4EMEN1LMNA | |
| Acetyltryptophanamide SCHEMBL3202823 | 0.89 | ECE1 (0.68) | ECE1HPGDSALOX15KDM4EMEN1 | |
| Acetyltryptophanamide SCHEMBL455277 | 0.89 | ECE1 (0.68) | ECE1HPGDSALOX15KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119517-A1 | COMPOSITIONS AND METHODS FOR PROTECTING AGAINST MITOCHONDRIA COMPONENT-MEDIATED PATHOLOGY | CORNELL RESEARCH FOUNDATION, INC. (US) | 2008-05-22 | — | — | US | disclosed |