Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | ACE | P12821 | 3/20 | 0.70 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.67 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.67 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.67 |
| ▸ | ITGAL | P20701 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | ECE1 | P42892 | 3/20 | 0.64 |
| ▸ | FPR2 | P25090 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29599837 | 1.00 | ALOX15 (0.71) | ALOX15ACEERAP2ITGB2ICAM1 | |
| SCHEMBL3829865 | 1.00 | ALOX15 (0.71) | ALOX15ACEERAP2ITGB2ICAM1 | |
| SCHEMBL5374217 | 1.00 | ALOX15 (0.71) | ALOX15ACEERAP2ITGB2ICAM1 | |
| SCHEMBL29865999 | 1.00 | ALOX15 (0.71) | ALOX15ACEERAP2ITGB2ICAM1 | |
| Hydrochloric Acid SCHEMBL27511139 | 0.99 | ALOX15 (0.70) | ALOX15ACEERAP2ITGB2ICAM1 | |
| SCHEMBL14213192 | 0.90 | ECE1 (0.67) | ALOX15ACEERAP2ITGB2ICAM1 | |
| SCHEMBL3857226 | 0.89 | ALOX15 (0.74) | ALOX15ACEERAP2ITGB2ICAM1 | |
| SCHEMBL3857229 | 0.89 | ALOX15 (0.74) | ALOX15ACEERAP2ITGB2ICAM1 | |
| Urea SCHEMBL2597753 | 0.87 | ERAP2 (0.65) | ALOX15ACEERAP2ITGB2ICAM1 | |
| Urea SCHEMBL2597752 | 0.87 | ERAP2 (0.65) | ALOX15ACEERAP2ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209234-A1 | STEREOSTRUCTURE OF DECARBAMYLASE AND METHOD OF USING THE SAME | Kaneka Corporation (JP) | 2002-05-29 | — | — | EP | claimed |
| EP-0159866-B1 | PROCESS FOR PRODUCTION OF L-AMINO ACIDS | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0159866-A2 | Process for production of L-amino acids | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-10-30 | — | — | EP | claimed |
| JP-61009293-A | — | — | None | — | — | JP | disclosed |
| JP-59005113-A | — | — | None | — | — | JP | disclosed |
| CN-114686464-B | Application of D-N-carbamyl hydrolase in production of D-tryptophan | 湖南引航生物科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115772513-A | D-carbamyl hydrolase mutant, gene, expression vector and application thereof | 江南大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-114686464-A | Application of D-N-carbamyl hydrolase in production of D-tryptophan | 湖南引航生物科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-109468304-B | Hydantoinase mutants | 赢创运营有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-10822627-B2 | Mutants of hydantoinase | EVONIK OPERATIONS GMBH (DE) | 2020-11-03 | — | — | US | disclosed |
| CN-111454933-A | D-carbamoyl hydrolase mutant and application thereof in synthesis of D-aromatic amino acid | 江南大学 | 2020-07-28 | — | — | CN | disclosed |
| US-5108914-A | Cleaving 5-substituted hydrantoins; nondegradable enzyme inductors o fhydantoins or diketopyrrolidines | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1992-04-28 | — | — | US | disclosed |
| EP-0273689-B1 | DERIVATIVES OF N-(2-ALKYL-3-MERCAPTO-GLUTARYL) ALPHA-AMINO ACIDS AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1991-11-27 | — | — | EP | disclosed |
| EP-0159866-B1 | PROCESS FOR PRODUCTION OF L-AMINO ACIDS | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0377083-A1 | Process to produce L-alpha-amino acids | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1990-07-11 | — | — | EP | disclosed |
| US-4937243-A | TREATING CONNECTIVE TISSUE DISEASES | BEECHAM GROUP P.L.C. (GB) | 1990-06-26 | — | — | US | disclosed |
| EP-0273689-A2 | Derivatives of N-(2-alkyl-3-mercapto-glutaryl) alpha-amino acids and their use as collagenase inhibitors | BEECHAM GROUP PLC (GB) | 1988-07-06 | — | — | EP | disclosed |
| JP-S619293-A | PRODUCTION OF L-AMINO ACID | DENKI KAGAKU KOGYO KK | 1986-01-16 | — | — | JP | disclosed |
| EP-0159866-A2 | Process for production of L-amino acids | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-10-30 | — | — | EP | disclosed |
| JP-S595113-A | PREPARATION OF AMINO ACID INJECTION CONTAINING REDUCING SUGAR | MOHAN YAKUHIN KENKYUSHO:KK | 1984-01-12 | — | — | JP | disclosed |