SCHEMBL14213193

SCHEMBL14213193

O=C(O)c1ccc(-c2ccc(C(=O)O)cc2F)c(F)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
MAPK1 P28482 1/20 0.57
HTT P42858 1/20 0.57
RAB9A P51151 1/20 0.57
RARB P10826 1/20 0.51
TTR P02766 3/20 0.50
TSHR P16473 2/20 0.50
ADH5 P11766 1/20 0.50
SLC22A12 Q96S37 1/20 0.50
TP53 P04637 1/20 0.50
AXL P30530 1/20 0.49
PTPRC P08575 2/20 0.48
KDM4E B2RXH2 2/20 0.48
POLB P06746 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
CA4 P22748 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5728663 0.90 TTR (0.56) LMNAMAPK1HTTRAB9ARARB
SCHEMBL6252810 0.87 RARB (0.61) LMNAMAPK1HTTRAB9ARARB
SCHEMBL2041007 0.86 RARB (0.56) LMNARARBTTRTSHRADH5
SCHEMBL29473809 0.86 RARB (0.56) LMNARARBTTRTSHRADH5
SCHEMBL14917120 0.84 RARB (0.51) LMNAMAPK1HTTRAB9ARARB
SCHEMBL26572449 0.84 BCL2L1 (0.62) LMNAMAPK1HTTRAB9ARARB
SCHEMBL30189377 0.84 RARB (0.51) LMNAMAPK1HTTRAB9ARARB
SCHEMBL15419853 0.84 RARB (0.51) LMNAMAPK1HTTRAB9ARARB
SCHEMBL29349680 0.83 CES2 (0.70) LMNAMAPK1HTTRAB9ATTR
SCHEMBL27151 0.83 CES2 (0.70) LMNAMAPK1HTTRAB9ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994907-A Light-weight high-strength flexible polyarylene sulfide composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-11-22 CN claimed
CN-116655936-A Eu-MOF probe material, preparation method thereof and application thereof in miRNA detection 南京晓庄学院 2023-08-29 CN claimed
CN-116655936-A Eu-MOF probe material, preparation method thereof and application thereof in miRNA detection 南京晓庄学院 2023-08-29 CN disclosed
US-7368216-B2 Photosensitive resin composition and manufacturing method of semiconductor device using the same FUJIFILM CORPORATION (JP) 2008-05-06 US disclosed
US-20070254243-A1 METHOD FOR MANUFACTURING PHOTOSENSITIVE RESIN COMPOSITION AND RELIEF PATTERN USING THE SAME FUJIFILM CORPORATION (JP) 2007-11-01 US disclosed
US-20070254243-A1 METHOD FOR MANUFACTURING PHOTOSENSITIVE RESIN COMPOSITION AND RELIEF PATTERN USING THE SAME FUJIFILM CORPORATION (JP) 2007-11-01 US disclosed
US-20070172753-A1 Photosensitive resin composition and manufacturing method of semiconductor device using the same FUJIFILM CORPORATION (JP) 2007-07-26 US disclosed