SCHEMBL27151

SCHEMBL27151

O=C(O)c1ccc(F)c(F)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.70
CES1 P23141 2/20 0.70
LMNA P02545 2/20 0.59
MAPK1 P28482 1/20 0.59
HTT P42858 1/20 0.59
RAB9A P51151 1/20 0.59
KDM4E B2RXH2 3/20 0.54
GAA P10253 2/20 0.54
HSD17B10 Q99714 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
GFER P55789 1/20 0.54
TSHR P16473 3/20 0.52
TP53 P04637 1/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
CA4 P22748 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349680 1.00 CES2 (0.70) CES2CES1LMNAMAPK1HTT
Hydrochloric Acid SCHEMBL31439035 0.98 CES2 (0.67) CES2CES1LMNAMAPK1HTT
Hydrochloric Acid SCHEMBL10557218 0.98 CES2 (0.67) CES2CES1LMNAMAPK1HTT
Hydrochloric Acid SCHEMBL31439055 0.98 CES2 (0.67) CES2CES1LMNAMAPK1HTT
SCHEMBL14213193 0.83 LMNA (0.57) CES2CES1LMNAMAPK1HTT
SCHEMBL2247505 0.82 KDM4E (0.72) CES2CES1LMNAKDM4EHSD17B10
SCHEMBL29798141 0.82 CES1 (1.00) CES2CES1RAB9AMEN1KMT2A
SCHEMBL7967901 0.82 CES2 (0.73) CES2CES1RAB9AMEN1KMT2A
SCHEMBL3556449 0.81 CES2 (0.78) CES2CES1LMNAMAPK1HTT
SCHEMBL336060 0.81 KDM4E (0.52) CES2CES1LMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
US-20250347195-A1 OPTIMIZING CO2 GEOSEQUESTRATION WITH RESPONSIVE TRACERS ARAMCO SERVICES COMPANY (US) 2025-11-13 US claimed
EP-4634196-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES Momentive Performance Materials GmbH (DE) 2025-10-22 EP claimed
WO-2025202864-A1 ENT1 INHIBITORS IN COMBINATION WITH ONCOLYTIC VIRUSES AND THEIR USE IN THE TREATMENT OF CANCER iTeos Belgium SA (BE) 2025-10-02 WO claimed
WO-2025126110-A1 ENT1 INHIBITORS IN COMBINATION WITH BISPECIFIC ANTIBODIES iTeos Belgium SA (BE) 2025-06-19 WO claimed
WO-2025104613-A1 ENT1 INHIBITORS IN COMBINATION WITH CHECKPOINT INHIBITORS iTeos Belgium SA (BE) 2025-05-22 WO claimed
WO-2024126692-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2024-06-20 WO claimed
CN-118164897-A Spirotemporal compound and preparation method and application thereof 南开大学 2024-06-11 CN claimed
US-11994020-B2 Mapping inter-well porosity using tracers with different transport properties SAUDI ARABIAN OIL COMPANY (SA) 2024-05-28 US claimed
US-20240093598-A1 MAPPING INTER-WELL POROSITY USING TRACERS WITH DIFFERENT TRANSPORT PROPERTIES ARAMCO SERVICES COMPANY (US) 2024-03-21 US claimed
WO-2002095189-A1 METHOD OF DETERMINING THE EXTENT OF RECOVERY OF MATERIALS INJECTED INTO OIL WELLS CORE LABORATORIES L.P. (US) 2002-11-28 WO claimed
US-6180830-B1 REDUCING COMPLEX OF RUTHENIUM HAVING ELECTROVALENCY OF-4 AND COORDINATION NUMBER OF 6, WHEREIN AT LEAST ONE LIGAND IS TIN HALIDE, OTHER LIGANDS OPTIONALLY BEING HALOGEN ATOMS RHODIA CHIMIE (FR) 2001-01-30 US claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 EP claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
EP-0429848-A2 Preparation of 3,4-difluorobenzoic acid by the decarboxylation of 4,5-difluorophthalic anhydride or 4,5-difluorophthalic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1991-06-05 EP claimed
US-5003103-A Decarboxylation, chlorodenitration, catalysis OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-26 US claimed
US-4994606-A Decarboxylating 4,5-difluorophthalic anhydride by heating in dimethyl acetamide; nitration, reduction OCCIDENTAL CHEMICAL CORPORATION (US) 1991-02-19 US claimed
US-4937377-A HEATING IN A SOLVENT SELECTED FROM DIMETHYLACETAMIDE, METHYL PYRROLIDONE AND QUINOLINE OCCIDENTAL CHEMICAL CORPORATION (US) 1990-06-26 US claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed