Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605502 | 0.79 | HTT (0.38) | PIK3CGIDH1 | |
| SCHEMBL9449998 | 0.76 | PIK3CG (0.34) | PIK3CGIDH1 | |
| SCHEMBL10147793 | 0.76 | PIK3CG (0.34) | PIK3CGIDH1 | |
| SCHEMBL20049385 | 0.76 | PIK3CG (0.34) | PIK3CGIDH1 | |
| SCHEMBL5388110 | 0.75 | PIK3CG (0.33) | PIK3CG | |
| SCHEMBL5388859 | 0.75 | PIK3CG (0.33) | PIK3CG | |
| SCHEMBL5388113 | 0.75 | PIK3CG (0.33) | PIK3CG | |
| SCHEMBL21180509 | 0.74 | PIK3CG (0.35) | PIK3CGIDH1 | |
| SCHEMBL15931976 | 0.74 | GPR119 (0.35) | — | |
| SCHEMBL469194 | 0.74 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684357-B1 | HETEROARYL ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| US-20120309750-A1 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | ILDONG PHARM CO., LTD. (KR) | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309750-A1 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | CYP3A5, UGT2B7, UGT1A7 | PIK3CG 1194/4885IDH1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.