SCHEMBL9449998

SCHEMBL9449998

CC(Cl)c1nc(C(C)(C)C)no1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.34
IDH1 O75874 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2605502 0.83 HTT (0.38) PIK3CGIDH1
SCHEMBL10147793 0.79 PIK3CG (0.34) PIK3CGIDH1
SCHEMBL20049385 0.79 PIK3CG (0.34) PIK3CGIDH1
SCHEMBL21180509 0.77 PIK3CG (0.35) PIK3CGIDH1
SCHEMBL14213299 0.76 PIK3CG (0.33) PIK3CGIDH1
SCHEMBL24704040 0.75 PIK3CG (0.32) PIK3CGIDH1
SCHEMBL20049229 0.75 PIK3CG (0.32) PIK3CGIDH1
SCHEMBL23490727 0.73 PIK3CG (0.33) PIK3CGIDH1
SCHEMBL9449604 0.71
SCHEMBL9449631 0.70 GPR119 (0.36) IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5207819-A Herbicides AGRO-KANESHO CO., LTD (JP) 1993-05-04 US disclosed
EP-0288275-B1 PHENOXYPROPIONIC ACID DERIVATIVES FOR USE AS HERBICIDES Tosoh Corporation (JP) 1993-01-27 EP disclosed
US-4948421-A INHIBITS WEEDS BELONGING TO FAMILY GRAMINEAE TOSOH CORPORATION (JP) 1990-08-14 US disclosed
EP-0288275-A2 Phenoxypropionic acid derivatives for use as herbicides Tosoh Corporation (JP) 1988-10-26 EP disclosed
US-4497804-A Insecticidal, acaricidal, and nematicidal O-ethyl S-alkyl S-(1,2,4-oxadiazol-5-yl-methyl) phosphorodithiolate derivatives, compositions, and methods of use NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-02-05 US disclosed
EP-0081151-A1 Organophosphates, process for preparing them and pesticides containing them NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1983-06-15 EP disclosed