Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24130013 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL1809204 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL9315098 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL9315107 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL1515627 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL3712256 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL18471505 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL26795644 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL3874355 | 0.77 | EGFR (0.59) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 | |
| SCHEMBL18407332 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPK1EGFRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309750-A1 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | ILDONG PHARM CO., LTD. (KR) | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309750-A1 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND MANUFACTURING PROCESS THEREOF | CYP3A5, UGT2B7, UGT1A7 | ALDH1A1 590/4885MAPK1 1492/4885EGFR 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.