SCHEMBL142135

SCHEMBL142135

Nc1cc(Cl)c(-c2cc(Cl)c(N)cc2Cl)cc1Cl

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.75
AHR P35869 3/20 0.56
MAPK1 P28482 2/20 0.56
TSHR P16473 5/20 0.43
CYP3A4 P08684 5/20 0.43
TP53 P04637 1/20 0.43
CD44 P16070 1/20 0.43
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 3/20 0.42
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA5B Q9Y2D0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8641891 0.97 GAA (0.71) GAAAHRMAPK1TSHRCYP3A4
SCHEMBL64092 0.87 GAA (1.00) GAAMAPK1TSHRCYP3A4TP53
SCHEMBL9973085 0.85 CD44 (0.62) GAAAHRMAPK1TSHRCYP3A4
Sulfuric Acid SCHEMBL8642518 0.85 ALDH1A1 (0.55) GAAAHRMAPK1TSHRCYP3A4
SCHEMBL12775035 0.85 GAA (0.55) GAAAHRMAPK1TSHRCYP3A4
SCHEMBL18215158 0.83 CYP3A4 (0.71) GAAAHRMAPK1TSHRCYP3A4
Hydrochloric Acid SCHEMBL28016984 0.83 GAA (0.92) GAAMAPK1TSHRCYP3A4TP53
SCHEMBL7085831 0.82 AHR (0.67) GAAAHRMAPK1TSHRCYP3A4
SCHEMBL9469367 0.82 GAA (0.50) GAAAHRMAPK1TSHRCYP3A4
SCHEMBL204719 0.80 GAA (0.86) GAAAHRMAPK1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405453-B1 A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2024-05-29 EP claimed
EP-3733409-B1 POLYAMIDE FILM LAMINATE LG CHEMICAL LTD (KR) 2024-04-17 EP claimed
US-11958987-B2 Cover window for flexible display device and flexible display device LG CHEM, LTD. (KR) 2024-04-16 US claimed
US-11926702-B2 Polyamide block copolymer and polyamide film including the same LG CHEM, LTD. (KR) 2024-03-12 US claimed
US-20230303786-A1 ULTRA-HIGH MODULUS AND HIGH-TRANSMITTANCE POLYIMIDE THIN FILM, AND PREPARATION METHOD AND APPLICATION THEREFOR RAYITEK HI-TECH FILM COMPANY, LTD., SHENZHEN (CN) 2023-09-28 US claimed
CN-112203853-B Cover window for flexible display device and flexible display device 株式会社LG化学 2022-11-18 CN claimed
US-11383485-B2 Plastic laminated film LG CHEM, LTD. (KR) 2022-07-12 US claimed
CN-112390949-B High-refractive-index polyimide light diffusant for epoxy resin 艾森半导体材料(南通)有限公司 2022-06-28 CN claimed
US-11351763-B2 Polyamide film laminate LG CHEM, LTD. (KR) 2022-06-07 US claimed
US-20220093680-A1 DISPLAY SUBSTRATE CHANGSUNG SHEET CO., LTD. (KR) 2022-03-24 US claimed
EP-1229066-A1 Photoactive polymer Rolic AG (CH) 2002-08-07 EP claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
EP-1195411-A1 Process for the preparation of azo colourants Clariant GmbH (DE) 2002-04-10 EP claimed
US-6067139-A SUPER TWISTED NEMATIC LIQUID CRYSTAL DISPLAY (STN LCD), HAVING AT LEAST TWO DOMAINS PER PIXEL, (MULTI-DOMAIN STN LCDS), USING A FLUORINATED POLYIMIDE ALIGNMENT FILM WHICH MAINTAINS A STABLE TILT ANGLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-23 US claimed
US-5478914-A Polyimides and processes for preparaing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-12-26 US claimed
US-5399655-A Acid-labile poly(amic acetal ester) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US claimed
US-5276132-A Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-01-04 US claimed
US-5194597-A PREPARATION OF A COUPLING PRODUCT OF BISIAZOTIZED 2,2',5,5'-TETRACHLORO-4,4'-DIAMINOBIPHENYL WITH TWO EQUIVALENTS OF N-ACETOACETYL-2,4-DIMETHYLANILIDE HOECHST AG (DE) 1993-03-16 US claimed
US-4002584-A LONG CHAIN POLYOL, HALOGENATED AROMATIC DIAMINE, ONE-SHOT REACTION IHARA CHEMICAL KOGYO KABUSHIKI KAISHA (JA) 1977-01-11 US claimed
US-3941768-A One step diazotization coupling process CIBA-GEIGY AG (CH) 1976-03-02 US claimed