SCHEMBL64092

SCHEMBL64092

Nc1cc(Cl)c(N)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 1.00
TSHR P16473 7/20 0.53
CYP3A4 P08684 7/20 0.53
TP53 P04637 1/20 0.53
CD44 P16070 1/20 0.53
ALDH1A1 P00352 4/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 1/20 0.50
CA12 O43570 3/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
PTK2 Q05397 1/20 0.43
CA4 P22748 2/20 0.42
CA6 P23280 2/20 0.42
CA5A P35218 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
CA3 P07451 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28016984 0.96 GAA (0.92) GAATSHRCYP3A4TP53CD44
SCHEMBL204719 0.93 GAA (0.86) GAATSHRCYP3A4TP53CD44
SCHEMBL398461 0.88 GAA (0.79) GAATSHRCYP3A4TP53CD44
SCHEMBL5492502 0.88 GAA (0.79) GAATSHRCYP3A4TP53CD44
SCHEMBL142135 0.87 GAA (0.75) GAATSHRCYP3A4TP53CD44
Hydrochloric Acid SCHEMBL8641891 0.84 GAA (0.71) GAATSHRCYP3A4TP53CD44
SCHEMBL8836502 0.84 GAA (0.71) GAATSHRCYP3A4TP53CD44
SCHEMBL29534050 0.83 GAA (0.71) GAATSHRCYP3A4TP53CD44
SCHEMBL203217 0.83 GAA (0.71) GAATSHRCYP3A4TP53CD44
SCHEMBL26746409 0.82 GAA (0.69) GAATSHRCYP3A4TP53CD44

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059171-A Preparation method, powder product and application of high molecular weight heterocyclic aromatic polyamide powder 中蓝晨光化工研究设计院有限公司 2025-05-30 CN claimed
CN-120059070-A Preparation method of hydrogel with covalent organic framework-polymer mechanical interlocking structure 河北工业大学 2025-05-30 CN claimed
CN-119842034-A Chlorine-containing COFs solid electrolyte and preparation method and application thereof 内蒙古工业大学 2025-04-18 CN claimed
CN-119265732-A High-strength high-toughness modified para-aramid fiber and preparation method thereof 江苏盛邦新材股份有限公司 2025-01-07 CN claimed
CN-118620155-A Preparation method and application of asymmetric two-dimensional imine covalent organic framework 南昌大学 2024-09-10 CN claimed
CN-118598757-A Synthesis method of 2, 5-dichloro-p-phenylenediamine 大连新阳光材料科技有限公司 2024-09-06 CN claimed
US-20240209150-A1 PREPARATION METHOD OF A HIGH-ENTROPY COVALENT ORGANIC FRAMEWORK COMPOUND CHINA THREE GORGES UNIVERSITY (CN) 2024-06-27 US claimed
CN-118142582-A Synthesis method and application of bio-fuel catalyst prepared based on Covalent Organic Frameworks (COFs) porous expandable structure 合肥飞木生物科技有限公司 2024-06-07 CN claimed
CN-118007259-A Preparation method of para-position copolymerized aramid fiber 河北金力新能源科技股份有限公司 2024-05-10 CN claimed
CN-118002203-A Preparation method and application of spinel-covalent organic framework composite material 河北工业大学 2024-05-10 CN claimed
EP-1021595-A2 ELECTROSYNTHESIS OF HYDROXYLAMMONIUM SALTS AND HYDROXYLAMINE USING A MEDIATOR, A CATALYTIC FILM, METHODS OF MAKING THE CATALYTIC FILM, AND ELECTROSYNTHESIS OF COMPOUNDS USING THE CATALYTIC FILM SACHEM, INC. (US) 2000-07-26 EP claimed
US-6067139-A SUPER TWISTED NEMATIC LIQUID CRYSTAL DISPLAY (STN LCD), HAVING AT LEAST TWO DOMAINS PER PIXEL, (MULTI-DOMAIN STN LCDS), USING A FLUORINATED POLYIMIDE ALIGNMENT FILM WHICH MAINTAINS A STABLE TILT ANGLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-23 US claimed
US-6024855-A Electrosynthesis of hydroxylammonium salts and hydroxylamine using a mediator SACHEM, INC. (US) 2000-02-15 US claimed
WO-1999009234-A2 ELECTROSYNTHESIS OF HYDROXYLAMMONIUM SALTS AND HYDROXYLAMINE USING A MEDIATOR, A CATALYTIC FILM, METHODS OF MAKING THE CATALYTIC FILM, AND ELECTROSYNTHESIS OF COMPOUNDS USING THE CATALYTIC FILM SACHEM, INC. (US) 1999-02-25 WO claimed
WO-1996001862-A1 METHODS FOR THE PREPARATION OF INHERENTLY METAL BINDING POLY-AMINE-QUINONE POLYMERS ERHAN SEMIH (US) 1996-01-25 WO claimed
US-5399655-A Acid-labile poly(amic acetal ester) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US claimed
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
US-5068292-A Reaction of monomers to form rigid polymer rods followed by reaction of matrix polymers in situ GENCORP INC. (US) 1991-11-26 US claimed
EP-0408166-A2 Composite polymeric materials GENCORP INC. (US) 1991-01-16 EP claimed
EP-0317943-A2 Polymers prepared from 4,4'-bis-[2-(3,4-(dicarboxyphenyl) hexafluoroisopropyl] diphenyl ether dianhydride HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed