Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.71 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.71 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.71 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.61 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213704 | 0.87 | CASP3 (0.54) | CASP3SENP8SENP7SENP6CHEK2 | |
| SCHEMBL29941485 | 0.83 | CASP3 (1.00) | CASP3SENP8SENP7SENP6CHEK2 | |
| SCHEMBL3704691 | 0.83 | CASP3 (1.00) | CASP3SENP8SENP7SENP6CHEK2 | |
| SCHEMBL8522621 | 0.79 | CASP3 (0.69) | CASP3SENP8SENP7SENP6CHEK2 | |
| SCHEMBL5438780 | 0.79 | CHEK2 (0.70) | CASP3SENP8SENP7SENP6CHEK2 | |
| SCHEMBL4876408 | 0.78 | CASP3 (0.68) | CASP3SENP8SENP7SENP6CHEK2 | |
| SCHEMBL14213713 | 0.78 | CYP19A1 (0.47) | CASP3SENP8SENP7SENP6CHEK2 | |
| SCHEMBL14190746 | 0.76 | CHEK2 (1.00) | CASP3SENP8SENP7SENP6CHEK2 | |
| SCHEMBL28163370 | 0.75 | NPC1 (0.65) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL31326256 | 0.75 | CASP3 (0.63) | CASP3SENP8SENP7SENP6CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |