SCHEMBL14213756

SCHEMBL14213756

CC(=O)CCC(F)(F)C(F)F

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.35
SLC15A2 Q16348 1/20 0.35
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
ACHE P22303 1/20 0.30
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10144848 0.86 ALDH1A1 (0.38) ALDH1A1LMNASLC15A2ACHEPAOX
SCHEMBL25858192 0.76 TSHR (0.48) ALDH1A1LMNAPOLBGAA
SCHEMBL14213754 0.75 ALDH1A1 (0.32) ALDH1A1
SCHEMBL6647762 0.74
SCHEMBL19859965 0.72
SCHEMBL15402829 0.72
SCHEMBL25982449 0.71 POLB (0.32) ALDH1A1LMNAPOLBGAA
SCHEMBL16885827 0.71
SCHEMBL210760 0.71 TET2 (0.38)
SCHEMBL15403083 0.71 CYP2C19 (0.39) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329344-B2 Fluorinated, acyclic carbonate derivatives; electrolytic double layer capacitor; excellent flame retardance, low temperature characteristics, withstand voltage, high solubility of an electrolyte salt; excellent compatibility with a hydrocarbon solvent DAIKIN INDUSTRIES, LTD. (JP) 2012-12-11 US disclosed