SCHEMBL14213754

SCHEMBL14213754

CC(=O)CC(F)(F)C(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15674992 0.76 ACLY (0.41) ALDH1A1TDP1
SCHEMBL14213756 0.75 ALDH1A1 (0.41) ALDH1A1
SCHEMBL11212211 0.75 GRIK1 (0.39)
SCHEMBL12096854 0.74
SCHEMBL25858122 0.73 TSHR (0.40) ALDH1A1
SCHEMBL9700927 0.72 ALDH1A1 (0.35) ALDH1A1
SCHEMBL5945784 0.72 POLB (0.31) ALDH1A1TDP1
SCHEMBL5945788 0.72 POLB (0.31) ALDH1A1TDP1
SCHEMBL10144848 0.72 ALDH1A1 (0.38) ALDH1A1
SCHEMBL8534509 0.71 ALDH1A1 (0.39) ALDH1A1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329344-B2 Fluorinated, acyclic carbonate derivatives; electrolytic double layer capacitor; excellent flame retardance, low temperature characteristics, withstand voltage, high solubility of an electrolyte salt; excellent compatibility with a hydrocarbon solvent DAIKIN INDUSTRIES, LTD. (JP) 2012-12-11 US disclosed