Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CFB | P00751 | 1/20 | 0.36 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 8/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178173 | 0.83 | CD38 (0.36) | ENPP2CFBEEDSUZ12EZH2 | |
| SCHEMBL10014958 | 0.78 | TAAR1 (0.45) | TAAR1CFBADRA2AADRA1AKMT2A | |
| SCHEMBL1178471 | 0.69 | MEN1 (0.34) | CFBADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL1178520 | 0.69 | TAAR1 (0.47) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL15984268 | 0.68 | ENPP2 (0.37) | ENPP2JAK2JAK3JAK1MEN1 | |
| SCHEMBL19967324 | 0.67 | MEN1 (0.50) | ENPP2JAK2JAK3JAK1MEN1 | |
| SCHEMBL8348698 | 0.67 | TAAR1 (0.34) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL1179567 | 0.67 | CFB (0.39) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL2023829 | 0.66 | ADRA2A (0.50) | CFBADRA2AKMT2AADRA2BADRA2C | |
| SCHEMBL1178570 | 0.66 | GSK3B (0.44) | JAK2JAK3ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329918-B2 | Selective alpha 2B/2C agonists | ALLERGAN INC. (US) | 2012-12-11 | — | — | US | disclosed |