Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4909409 | 0.82 | ROCK2 (0.33) | ROCK2ROCK1 | |
| SCHEMBL4904846 | 0.81 | BRD4 (0.33) | ROCK2ROCK1 | |
| SCHEMBL4906869 | 0.78 | ROCK2 (0.46) | ROCK2ROCK1 | |
| SCHEMBL13060371 | 0.70 | JAK2 (0.31) | — | |
| SCHEMBL14183645 | 0.66 | IGF1R (0.41) | — | |
| SCHEMBL14214190 | 0.65 | KDM4E (0.36) | — | |
| SCHEMBL91111 | 0.65 | GSK3B (0.35) | — | |
| SCHEMBL29056284 | 0.65 | PDE4B (0.41) | ROCK2 | |
| SCHEMBL10073622 | 0.64 | — | — | |
| SCHEMBL4909730 | 0.62 | IGF1R (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113946-A1 | N-aryl-5,7-dihydrofuro[3,4-d]pyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYNTOVIA, INC. (US) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113946-A1 | N-aryl-5,7-dihydrofuro[3,4-d]pyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP7, API5, CASP5 | ROCK2 3024/4885ROCK1 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.