Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755053 | 0.80 | MEN1 (0.50) | ESR2ESR1DRD1MEN1KMT2A | |
| SCHEMBL10772499 | 0.80 | ESR1 (0.70) | ESR2ESR1KIF11MEN1KMT2A | |
| SCHEMBL26136547 | 0.80 | ESR1 (0.70) | ESR2ESR1KIF11MEN1KMT2A | |
| SCHEMBL12004872 | 0.80 | ESR1 (0.70) | ESR2ESR1KIF11MEN1KMT2A | |
| SCHEMBL10774251 | 0.79 | ESR2 (0.73) | ESR2ESR1KIF11MEN1KMT2A | |
| SCHEMBL12541779 | 0.79 | ESR1 (0.53) | ESR2ESR1PTPN5MEN1KMT2A | |
| SCHEMBL13264261 | 0.75 | DRD1 (0.68) | DRD1MEN1KMT2AALOX15GFER | |
| SCHEMBL23082207 | 0.75 | ESR2 (0.63) | ESR2ESR1KIF11MEN1KMT2A | |
| SCHEMBL13906278 | 0.74 | DRD1 (0.53) | DRD1KIF11PTPN5MEN1KMT2A | |
| SCHEMBL8254927 | 0.74 | TP53 (0.49) | DRD1MEN1KMT2AALOX15GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080114183-A1 | Monomers comprising superacidic groups, and polymers therefrom | GENERAL ELECTRIC COMPANY (US) | 2008-05-15 | — | — | US | disclosed |
| US-20080114149-A1 | Polymers comprising superacidic groups, and uses thereof | GENERAL ELECTRIC COMPANY (US) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114183-A1 | Monomers comprising superacidic groups, and polymers therefrom | DDC, ACMSD, ALKBH3 | ESR2 4001/4885ESR1 1278/4885DRD1 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.