Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.57 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.57 |
| ▸ | TEK | Q02763 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 4/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.55 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14214557 | 0.83 | EPHB4 (0.59) | IGF1REPHB4TEKKDRAURKB | |
| SCHEMBL14214679 | 0.81 | PRKD3 (0.69) | IGF1REPHB4TEKKDRAURKB | |
| SCHEMBL2322576 | 0.81 | EPHB4 (0.59) | IGF1REPHB4TEKKDRAURKB | |
| SCHEMBL14214559 | 0.80 | TEK (0.52) | IGF1REPHB4TEKKDRAURKB | |
| SCHEMBL2281989 | 0.77 | AURKB (0.67) | IGF1REPHB4TEKKDRAURKB | |
| SCHEMBL21204434 | 0.76 | TBK1 (0.78) | TBK1JAK2 | |
| SCHEMBL6479711 | 0.76 | TEK (0.73) | IGF1REPHB4TEKKDRAURKB | |
| SCHEMBL14214558 | 0.76 | ZAP70 (0.73) | TEKTBK1EGFRLCKPRKD3 | |
| SCHEMBL14214684 | 0.76 | ZAP70 (0.73) | IGF1REPHB4TEKKDRAURKB | |
| SCHEMBL6480192 | 0.75 | IGF1R (0.65) | IGF1REPHB4TEKKDRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218360-B1 | TRIAZINE KINASE INHIBITORS | AMGEN INC (US) | 2008-05-28 | — | — | EP | disclosed |