Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 10/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4988506 | 0.85 | OXTR (0.40) | OXTRAVPR1AGRM5KDM4EALDH1A1 | |
| SCHEMBL4986965 | 0.84 | OXTR (0.39) | OXTRAVPR1AGRM5KDM4EALDH1A1 | |
| SCHEMBL14215092 | 0.83 | OXTR (0.46) | OXTRAVPR1ACHRNB2CHRNA4MEN1 | |
| SCHEMBL4987232 | 0.80 | AR (0.40) | OXTRAVPR1AKDM4EALDH1A1MEN1 | |
| SCHEMBL4987252 | 0.78 | OXTR (0.38) | OXTRAVPR1AKDM4EALDH1A1MEN1 | |
| SCHEMBL4987425 | 0.76 | HPGD (0.36) | OXTRAVPR1AALDH1A1HPGD | |
| SCHEMBL5524918 | 0.76 | RPA1 (0.47) | OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL14215387 | 0.76 | MEN1 (0.36) | OXTRAVPR1ACHRNB2CHRNA4MEN1 | |
| SCHEMBL29531456 | 0.76 | GRM5 (0.49) | OXTRGRM5KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL524681 | 0.76 | GRM5 (0.49) | OXTRGRM5KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | OXTR 2187/4885AVPR1A 548/4885GRM5 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.