SCHEMBL4987425

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5781022	0.90	HPGD (0.38)	HPGDPIK3CAPIK3CDPIK3R2PIK3CB
	SCHEMBL5785686	0.89	HPGD (0.38)	HPGDOXTRKCNH2AVPR1APIK3CA
	SCHEMBL5783378	0.88	LRRK2 (0.37)	HPGDPIK3CAPIK3CDPIK3R2PIK3CB
	SCHEMBL4982158	0.87	HPGD (0.39)	HPGDOXTRAVPR1APIK3CAPIK3CD
	SCHEMBL4984335	0.86	NNMT (0.44)	HPGDKCNH2PIK3CAPIK3CDPIK3R2
	SCHEMBL4982219	0.86	HPGD (0.36)	HPGDPIK3CAPIK3CDPIK3R2PIK3CB
	SCHEMBL4990225	0.86	HPGD (0.36)	HPGDPIK3CAPIK3CDPIK3R2PIK3CB
	SCHEMBL4987578	0.85	ALDH1A1 (0.39)	HPGDPIK3CAPIK3CDPIK3R2PIK3CB
	SCHEMBL4988214	0.83	HPGD (0.41)	HPGDKCNH2PIK3CAPIK3CDPIK3R2
	SCHEMBL4988506	0.83	OXTR (0.40)	HPGDKDM1AOXTRAVPR1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.