Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.45 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.45 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292246 | 0.89 | LMNA (0.52) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL4963754 | 0.89 | LMNA (0.52) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL12327664 | 0.89 | LMNA (0.52) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL4963759 | 0.89 | LMNA (0.52) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13539163 | 0.88 | TSHR (0.57) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL3856644 | 0.86 | LGALS9 (0.55) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL9462783 | 0.86 | LGALS9 (0.55) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL9767708 | 0.86 | LGALS9 (0.55) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL14215444 | 0.86 | LGALS9 (0.55) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL12858819 | 0.86 | LMNA (0.52) | TSHRLGALS9LGALS1LGALS3LGALS7; LGALS7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119373-A1 | Receptor Specific Binder Discovery Using Intramolecular Acyl Migration Induced Dynamic Carbohydrate Library | NEW YORK UNIVERSITY (US) | 2008-05-22 | — | — | US | disclosed |