Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18908668 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL24259722 | 0.86 | HPGD (0.50) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL23918721 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL24959969 | 0.84 | ALDH1A1 (0.38) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL25100443 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL19116931 | 0.78 | TP53 (0.52) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL23665086 | 0.78 | KMT2A (0.56) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL18716191 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL18199495 | 0.78 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL20340484 | 0.78 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1925320-A2 | Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics | Prolume, Ltd. (US) | 2008-05-28 | — | — | EP | disclosed |