Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14189112 | 0.78 | NOS2 (0.53) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| SCHEMBL15944878 | 0.74 | NOS2 (0.50) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| SCHEMBL8544170 | 0.73 | GRIN2B (0.53) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL16372137 | 0.71 | GRIN2B (0.61) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| SCHEMBL29293866 | 0.71 | NOS2 (0.55) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| SCHEMBL22068858 | 0.70 | NOS2 (0.65) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| SCHEMBL22068857 | 0.70 | NOS2 (0.65) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| SCHEMBL104888 | 0.70 | NOS2 (0.65) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| SCHEMBL16673266 | 0.69 | NOS2 (0.59) | NOS2GRIN2BGRIN1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL18045044 | 0.68 | NOS2 (0.57) | NOS2GRIN2BGRIN1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375088-B2 | Polyene polyketides, processes for their production and their use as a pharmaceutical | THALLION PHARMACEUTICALS INC. (CA) | 2008-05-20 | — | — | US | disclosed |