Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 13/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261144 | 0.82 | GRIN2B (0.47) | GRIN2BGRIN1NOS2GAANPC1 | |
| SCHEMBL28261143 | 0.82 | GRIN2B (0.47) | GRIN2BGRIN1NOS2GAANPC1 | |
| SCHEMBL18383468 | 0.82 | GRIN2B (0.47) | GRIN2BGRIN1NOS2GAANPC1 | |
| SCHEMBL14189112 | 0.78 | NOS2 (0.53) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL15944878 | 0.74 | NOS2 (0.50) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL164345 | 0.74 | GRIN2B (0.59) | GRIN2BGRIN1NOS2NPC1GRIN2D | |
| SCHEMBL2206812 | 0.74 | GRIN2B (0.59) | GRIN2BGRIN1NOS2NPC1GRIN2D | |
| SCHEMBL987917 | 0.74 | GRIN2B (0.59) | GRIN2BGRIN1NOS2NPC1GRIN2D | |
| SCHEMBL14215819 | 0.73 | NOS2 (0.48) | GRIN2BGRIN1NOS2GRIN2DGRIN3B | |
| SCHEMBL5075641 | 0.73 | GRIN2B (0.63) | GRIN2BGRIN1NOS2NPC1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671385-B1 | Method for handling (2-alkyl) acryloyl isocyanate, method for producing (2-alkyl)acryloyl isocyanate, heterocyclic compound, and method for producing heterocyclic compound | NIPPON PAINT CO LTD (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5663423-A | Method for handling (2-alkyl) (acryloyl) isocyanate, method for stabilizing (2-alkyl) (acryloyl) isocyanate, method for producing (2-alkyl) (acryloyl) isocyanate, heterocyclic compound, and method for producing heterocyclic compound | NIPPON PAINT CO., LTD (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5532360-A | REACTING WITH AZOMETHINE COMPOUND TO FORM HETEROCYCLIC COMPOUND | NIPPON PAINT CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0671385-A1 | Method for handling (2-alkyl) acryloyl isocyanate, method for producing (2-alkyl)acryloyl isocyanate, heterocyclic compound, and method for producing heterocyclic compound | Nippon Paint Co., Ltd. (JP) | 1995-09-13 | — | — | EP | disclosed |