Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614215 | 0.81 | APP (0.65) | APPKCNH2RELANFE2L2MAT2A | |
| SCHEMBL8295486 | 0.79 | CYP2A6 (0.64) | APPCYP2A6CYP1A2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL27634827 | 0.77 | CYP2A6 (0.61) | APPCYP2A6CYP1A2MAPTALDH1A1 | |
| SCHEMBL900823 | 0.77 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL19003408 | 0.77 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL9678907 | 0.77 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL9680312 | 0.77 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL13264717 | 0.76 | APP (0.60) | APPCYP2A6CYP1A2RELAMAPT | |
| SCHEMBL14087151 | 0.73 | CYP1A2 (0.62) | APPCYP2A6CYP1A2MAPTALDH1A1 | |
| SCHEMBL10031855 | 0.73 | RELA (0.52) | CYP2A6CYP1A2RELANFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108840-A1 | Stilbene Derivatives And Their Use For Binding And Imaging Amyloid Plaques | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108840-A1 | Stilbene Derivatives And Their Use For Binding And Imaging Amyloid Plaques | APP, APBA1, PSEN1 | APP 1/4885CYP2A6 4822/4885CYP1A2 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.