SCHEMBL8295486

SCHEMBL8295486

CNc1ccc2ccc(C)cc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.64
CYP1A2 P05177 4/20 0.64
TDP1 Q9NUW8 1/20 0.50
APP P05067 2/20 0.41
SNCA P37840 2/20 0.41
MAPT P10636 2/20 0.41
EGFR P00533 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
LMNA P02545 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
USP2 O75604 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27634827 0.98 CYP2A6 (0.61) CYP2A6CYP1A2TDP1APPSNCA
SCHEMBL14087151 0.93 CYP1A2 (0.62) CYP2A6CYP1A2TDP1APPSNCA
Hydrochloric Acid SCHEMBL27615979 0.91 CYP1A2 (0.59) CYP2A6CYP1A2TDP1APPSNCA
SCHEMBL25973229 0.88 EGFR (0.47) CYP2A6CYP1A2APPMAPTEGFR
SCHEMBL25761244 0.80 CYP2A6 (0.47) CYP2A6CYP1A2TDP1APPSNCA
SCHEMBL8156941 0.80 EGFR (0.48) CYP2A6CYP1A2APPSNCAMAPT
SCHEMBL425085 0.80 CYP1A2 (1.00) CYP2A6CYP1A2TDP1MAPTLMNA
SCHEMBL29399131 0.80 CYP1A2 (1.00) CYP2A6CYP1A2TDP1MAPTLMNA
SCHEMBL14215833 0.79 APP (0.50) CYP2A6CYP1A2TDP1APPMAPT
SCHEMBL13577861 0.77 CYP2A6 (0.59) CYP2A6CYP1A2TDP1SNCAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312604-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-10-05 US disclosed
US-20230200209-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
CN-103298772-B Method for producing aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL CO 2015-06-24 CN disclosed
CN-103298772-A Method for producing aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL CO 2013-09-11 CN disclosed
EP-2105436-A1 Lactam-containing compounds and derivatives thereof as factor XA inhibitors Bristol-Myers Squibb Company (US) 2009-09-30 EP disclosed
US-7414129-B2 Reactive triphendioxazine dyes, methods for the production thereof, and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-08-19 US disclosed
US-7414129-B2 Reactive triphendioxazine dyes, methods for the production thereof, and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-08-19 US disclosed
US-20080114166-A1 Reactive Triphendioxazine Dyes, Methods for the Production Thereof, and Use Thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-05-15 US disclosed
US-20080114166-A1 Reactive Triphendioxazine Dyes, Methods for the Production Thereof, and Use Thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-05-15 US disclosed
WO-2004108892-A2 1,1-DISUBSTITUTEDCYCLOALKYL-, GLYCINAMIDYL-, SULFONYL-AMIDINO-, AND TETRAHYDROPYRIMIDINYL-CONTAINING DIAMINOALKYL, β-AMINOACIDS, α-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-12-16 WO disclosed
WO-2004083174-A2 SULFONYL-AMIDINO CONTAINING AND TETRAHYDROPYRIMIDINO CONTAINING COMPOUNDS AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-09-30 WO disclosed
WO-2004037176-A2 QUINAZOLINONES AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-05-06 WO disclosed
WO-2003099276-A1 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-12-04 WO disclosed
WO-2003047520-A2 SUBSTITUTED AMINO METHYL FACTOR Xa INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 WO disclosed
WO-2003026652-A1 LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-04-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230200209-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME CRY1, ZFX, PPOX CYP2A6 982/4885CYP1A2 523/4885TDP1 2316/4885
US-20080114166-A1 Reactive Triphendioxazine Dyes, Methods for the Production Thereof, and Use Thereof CYP4X1, CYP1A1, P2RX4 CYP2A6 213/4885CYP1A2 14/4885TDP1 457/4885
US-20230312604-A1 HETEROCYCLIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC DEVICE ODC1, LEF1, PIEZO1 CYP2A6 1310/4885CYP1A2 142/4885TDP1 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.