Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14216528 | 0.84 | AR (0.57) | PGRCYP3A4LMNAALDH1A1SHBG | |
| SCHEMBL11690298 | 0.81 | SERPINA6 (0.58) | PGRCYP3A4LMNAABCB11ALDH1A1 | |
| SCHEMBL13216473 | 0.76 | CYP3A4 (0.64) | PGRCYP3A4LMNAABCB11ALDH1A1 | |
| SCHEMBL11596660 | 0.76 | CYP3A4 (0.64) | PGRCYP3A4LMNAABCB11ALDH1A1 | |
| SCHEMBL11475742 | 0.76 | CYP3A4 (0.64) | PGRCYP3A4LMNAABCB11ALDH1A1 | |
| Normethandrone SCHEMBL23801610 | 0.76 | PGR (0.73) | PGRCYP3A4LMNAABCB11ALDH1A1 | |
| Normethandrone SCHEMBL148632 | 0.76 | PGR (0.73) | PGRCYP3A4LMNAABCB11ALDH1A1 | |
| Normethandrone SCHEMBL148631 | 0.76 | PGR (0.73) | PGRCYP3A4LMNAABCB11ALDH1A1 | |
| SCHEMBL10606405 | 0.75 | PGR (0.60) | PGRCYP3A4LMNAABCB11ALDH1A1 | |
| SCHEMBL11689567 | 0.74 | PGR (0.58) | PGRCYP3A4LMNAABCB11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343806-B1 | METHYLENE STEROIDS AS NOVEL ANDROGENS | ORGANON NV (NL) | 2008-05-28 | — | — | EP | disclosed |