Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.57 |
| ▸ | PGR | P06401 | 12/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14216486 | 0.86 | PDK1 (0.43) | ARPGRNR3C2SHBG | |
| SCHEMBL14216488 | 0.86 | PDK1 (0.43) | ARPGRNR3C2SHBG | |
| SCHEMBL14216532 | 0.84 | PGR (0.55) | ARPGRNR3C2SHBGLMNA | |
| SCHEMBL14216509 | 0.82 | AR (0.39) | ARPGRNR3C2 | |
| SCHEMBL7120650 | 0.81 | AR (0.63) | ARPGRNR3C2SHBGLMNA | |
| SCHEMBL5023928 | 0.81 | AR (0.63) | ARPGRNR3C2SHBGLMNA | |
| SCHEMBL5023925 | 0.81 | AR (0.63) | ARPGRNR3C2SHBGLMNA | |
| SCHEMBL24476181 | 0.80 | AR (0.62) | ARPGRNR3C2SHBGLMNA | |
| SCHEMBL6467277 | 0.80 | AR (0.62) | ARPGRNR3C2SHBGLMNA | |
| SCHEMBL6467275 | 0.80 | AR (0.62) | ARPGRNR3C2SHBGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343806-B1 | METHYLENE STEROIDS AS NOVEL ANDROGENS | ORGANON NV (NL) | 2008-05-28 | — | — | EP | disclosed |