Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15981079 | 0.85 | PPARD (0.54) | PPARDTSHRTP53TDP1 | |
| SCHEMBL13301492 | 0.83 | PPARD (0.52) | PPARDTSHRTP53TDP1 | |
| SCHEMBL3313657 | 0.83 | PPARD (0.70) | PPARDTSHRTP53TDP1MEN1 | |
| SCHEMBL248038 | 0.78 | PPARD (0.64) | PPARDTSHRTP53TDP1 | |
| SCHEMBL7268189 | 0.78 | PPARD (0.64) | PPARDTSHRTP53TDP1 | |
| SCHEMBL5017294 | 0.78 | PPARD (0.64) | PPARDTSHRTP53TDP1 | |
| SCHEMBL11514496 | 0.76 | PPARD (0.61) | PPARDTSHRTP53TDP1 | |
| SCHEMBL7268183 | 0.76 | PPARD (0.61) | PPARDTSHRTP53TDP1 | |
| SCHEMBL11323349 | 0.76 | PPARD (0.61) | PPARDTSHRTP53TDP1 | |
| SCHEMBL11127676 | 0.74 | PPARD (0.58) | PPARDTSHRTP53TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080114165-A1 | Methods for the Preparation of {2-[(8,9)-Dioxo-2,6-diaza-bicyclo[5.2.0]-non-1(7)-en-2-yl]ethyl} Phosphonic Acid and Esters Thereof | WYETH (US) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114165-A1 | Methods for the Preparation of {2-[(8,9)-Dioxo-2,6-diaza-bicyclo[5.2.0]-non-1(7)-en-2-yl]ethyl} Phosphonic Acid and Esters Thereof | PHOSPHO1, ENPP1, ENO1 | PPARD 805/4885TSHR 3472/4885TP53 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.