SCHEMBL5017294

SCHEMBL5017294

CCOP(=O)(CCCP(=O)(OCC)OCC)OCC

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.64
TSHR P16473 2/20 0.60
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7268189 0.94 PPARD (0.64) PPARDTSHRTP53TDP1
SCHEMBL11514496 0.92 PPARD (0.61) PPARDTSHRTP53TDP1
SCHEMBL11323349 0.92 PPARD (0.61) PPARDTSHRTP53TDP1
SCHEMBL7268183 0.92 PPARD (0.61) PPARDTSHRTP53TDP1
SCHEMBL11441759 0.90 PPARD (0.54) PPARDTSHRTP53TDP1
SCHEMBL575145 0.89 PPARD (0.58) PPARDTSHR
SCHEMBL8656736 0.88 PPARD (0.52) PPARDTSHRTP53TDP1
SCHEMBL21354224 0.88 PPARD (0.58) PPARDTSHRTDP1
SCHEMBL3313657 0.88 PPARD (0.70) PPARDTSHRTP53TDP1
SCHEMBL388266 0.87 PPARD (0.56) PPARDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669071-B Synthetic method of polyketone ligand 1, 3-bis [ bis (2-methoxyphenyl) phosphino ] propane 黄河三角洲京博化工研究院有限公司 2022-03-29 CN claimed
US-4141967-A ANHYDROUS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-02-27 US claimed
EP-4269543-B1 POLYSILOXANE HYDRAULIC FLUIDS COMMW SCIENT IND RES ORG (AU) 2026-03-04 EP disclosed
US-12227713-B2 Polysiloxane hydraulic fluids THE BOEING COMPANY (US) 2025-02-18 US disclosed
US-20250011671-A9 POLYSILOXANE HYDRAULIC FLUIDS THE BOEING COMPANY 2025-01-09 US disclosed
EP-3455282-B1 POLYSILOXANE HYDRAULIC FLUIDS COMMW SCIENT IND RES ORG (AU) 2023-11-01 EP disclosed
EP-4269543-A2 POLYSILOXANE HYDRAULIC FLUIDS Commonwealth Scientific and Industrial Research Organisation (AU) 2023-11-01 EP disclosed
US-20230323233-A1 POLYSILOXANE HYDRAULIC FLUIDS BOEING CO (US) 2023-10-12 US disclosed
US-20230323233-A1 POLYSILOXANE HYDRAULIC FLUIDS BOEING CO (US) 2023-10-12 US disclosed
US-20230323233-A1 POLYSILOXANE HYDRAULIC FLUIDS BOEING CO (US) 2023-10-12 US disclosed
US-11299688-B2 Polysiloxane hydraulic fluids THE BOEING COMPANY (US) 2022-04-12 US disclosed
US-6723882-B2 Preparation of dialkyl ketones BASF AKTIENGESELLSCHAFT (DE) 2004-04-20 US disclosed
US-20030191339-A1 Catalyst system and method for carbonylation BASF AKTIENGESELLSCHAFT (DE) 2003-10-09 US disclosed
US-20030069450-A1 Preparation of dialkyl ketones BASF AKTIENGESELLSCHAFT (DE) 2003-04-10 US disclosed
US-4902833-A Bisphosphine dioxides UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-02-20 US disclosed
EP-0173041-B1 2-SUBSTITUTED-1,3-PROPYLIDENEDIPHOSPHONATE DERIVATIVES, THE PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SYMPHAR S.A. (CH) 1988-11-30 EP disclosed
US-4696920-A CARDIOVASCULAR DISORDERS SYMPHAR S.A. (CH) 1987-09-29 US disclosed
EP-0173041-A1 2-Substituted-1,3-propylidenediphosphonate derivatives, the process for their preparation and pharmaceutical compositions containing them SYMPHAR S.A. (CH) 1986-03-05 EP disclosed
US-4141967-A ANHYDROUS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-02-27 US disclosed
US-4012294-A STABILITY OXY METAL INDUSTRIES CORPORATION (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069450-A1 Preparation of dialkyl ketones PDK2, PDK3, PDK4 PPARD 33/4885TSHR 2785/4885TP53 2919/4885
US-20030191339-A1 Catalyst system and method for carbonylation CBR3, PCCA, CBR1 PPARD 905/4885TSHR 4808/4885TP53 2605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.