SCHEMBL14217004 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ABL1	P00519	13/20	0.39

▸	SYK	P43405	1/20	0.39

▸	MAPK14	Q16539	2/20	0.37

▸	KDM4E	B2RXH2	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	HPGD	P15428	1/20	0.35

▸	HSD17B10	Q99714	1/20	0.35

▸	FGFR1	P11362	1/20	0.34

▸	SRC	P12931	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14217005	0.87	ABL1 (0.39)	ABL1SYKMAPK14KDM4EALDH1A1
SCHEMBL10043963	0.85	ABL1 (0.53)	ABL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL10043964	0.83	ABL1 (0.47)	ABL1SYKKDM4EALDH1A1HPGD
SCHEMBL14217006	0.83	ABL1 (0.39)	ABL1SYKMAPK14KDM4EALDH1A1
SCHEMBL10043738	0.82	KDM4E (0.56)	ABL1MAPK14KDM4EALDH1A1HPGD
SCHEMBL10043701	0.82	KDM4E (0.56)	ABL1MAPK14KDM4EALDH1A1HPGD
SCHEMBL10043968	0.81	ABL1 (0.48)	ABL1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL10043828	0.81	RAB9A (0.48)	ABL1SYKMAPK14KDM4EFGFR1
SCHEMBL10043965	0.80	ABL1 (0.39)	ABL1SYKMAPK14KDM4EALDH1A1
SCHEMBL14144989	0.80	CYP3A4 (0.43)	ABL1SYKMAPK14KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008051757-A1	COMPOSITIONS AND METHODS FOR MODULATING C-KIT AND PDGFR RECEPTORS	IRM LLC (BM)	2008-05-02	—	—	WO	disclosed