Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10043963 | 0.84 | ABL1 (0.53) | ABL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14217005 | 0.83 | ABL1 (0.39) | ABL1SYKKDM4EALDH1A1HPGD | |
| SCHEMBL14217004 | 0.83 | ABL1 (0.39) | ABL1SYKKDM4EALDH1A1HPGD | |
| SCHEMBL10043968 | 0.83 | ABL1 (0.48) | ABL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10043964 | 0.82 | ABL1 (0.47) | ABL1SYKKDM4EALDH1A1HPGD | |
| SCHEMBL10043738 | 0.81 | KDM4E (0.56) | ABL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10043701 | 0.81 | KDM4E (0.56) | ABL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10043828 | 0.80 | RAB9A (0.48) | ABL1SYKKDM4EMAPK14TP53 | |
| SCHEMBL10043965 | 0.79 | ABL1 (0.39) | ABL1SYKKDM4EALDH1A1HPGD | |
| SCHEMBL14144989 | 0.79 | CYP3A4 (0.43) | ABL1SYKKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008051757-A1 | COMPOSITIONS AND METHODS FOR MODULATING C-KIT AND PDGFR RECEPTORS | IRM LLC (BM) | 2008-05-02 | — | — | WO | disclosed |