Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ITGAM | P11215 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13108229 | 0.95 | NPC1 (0.40) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL13108226 | 0.90 | NPC1 (0.41) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL12900230 | 0.86 | INSR (0.40) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL12733759 | 0.85 | ADRB2 (0.37) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL13602008 | 0.85 | ADRB2 (0.37) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL14679240 | 0.85 | NPC1 (0.39) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL13232589 | 0.85 | NPC1 (0.54) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL13124538 | 0.84 | MEN1 (0.37) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL12139897 | 0.84 | INSR (0.43) | NPC1RAB9AUSP2MTORMEN1 | |
| SCHEMBL26845369 | 0.82 | ADRB2 (0.36) | NPC1RAB9AUSP2MTORMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1918709-A1 | Reagent, reagent kit and analyzing method | Sysmex Corporation (JP) | 2008-05-07 | — | — | EP | disclosed |