Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 8/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638253 | 0.89 | FAAH (0.39) | AKR1C3AKR1C2FAAHPTGS2LPAR1 | |
| SCHEMBL13638283 | 0.89 | FAAH (0.39) | FAAHPTGS2LPAR1LPAR5AGTR2 | |
| SCHEMBL13638254 | 0.84 | FAAH (0.36) | AKR1C3AKR1C2FAAHPTGS2LPAR1 | |
| SCHEMBL13638403 | 0.81 | LPAR1 (0.40) | LPAR1LPAR5 | |
| SCHEMBL13638171 | 0.77 | RARB (0.39) | LPAR1LPAR5AGTR2RARB | |
| SCHEMBL4073264 | 0.76 | PTGDR2 (0.38) | LPAR1LPAR5 | |
| SCHEMBL4493480 | 0.74 | F2 (0.39) | AKR1C3AKR1C2FAAHLPAR1LPAR5 | |
| SCHEMBL13638404 | 0.74 | MAPT (0.38) | AGTR2RARB | |
| SCHEMBL14252000 | 0.74 | LPAR1 (0.41) | LPAR1LPAR5 | |
| SCHEMBL13638168 | 0.73 | RARB (0.44) | LPAR1LPAR5RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059335-A1 | DIARYL, DIPYRIDINYL AND ARYL-PYRIDINYL DERIVATIVES AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2008-05-22 | — | — | WO | disclosed |