Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640790 | 1.00 | TAAR1 (0.47) | TAAR1CYP1A2CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL23242089 | 1.00 | TAAR1 (0.47) | TAAR1CYP1A2CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL21275431 | 1.00 | TAAR1 (0.47) | TAAR1CYP1A2CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL20037983 | 0.82 | LMNA (0.37) | CYP1A2CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL13003596 | 0.82 | KMT2A (0.41) | CYP1A2CYP2C19MEN1LMNAKMT2A | |
| SCHEMBL24501868 | 0.82 | KMT2A (0.41) | CYP1A2CYP2C19MEN1LMNAKMT2A | |
| SCHEMBL6745604 | 0.82 | KMT2A (0.41) | CYP1A2CYP2C19MEN1LMNAKMT2A | |
| SCHEMBL6075377 | 0.80 | TAAR1 (0.50) | TAAR1CYP1A2CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL18927429 | 0.78 | KMT2A (0.40) | CYP1A2CYP2E1CYP2A6CYP2B6CYP2C19 | |
| SCHEMBL3817150 | 0.78 | CYP3A4 (0.46) | TAAR1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661563-B1 | Compound effecting Glucokinase | ASTRAZENECA AB (SE) | 2008-05-28 | — | — | EP | disclosed |