Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 14/20 | 0.68 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.68 |
| ▸ | GABRA3 | P34903 | 14/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.68 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.68 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.68 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061778 | 0.86 | GABRA3 (0.70) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL19922700 | 0.85 | GABRG2 (0.71) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL8235774 | 0.85 | GABRG2 (0.50) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL10045479 | 0.84 | GABRG2 (0.77) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL637699 | 0.84 | GABRG2 (0.79) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL18096770 | 0.84 | GABRA3 (0.62) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL13966572 | 0.83 | GABRG2 (0.60) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL17088100 | 0.83 | GABRG2 (0.65) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL16638525 | 0.83 | GABRG2 (0.74) | GABRG2GABRB3GABRA3GABRA2GABRA1 | |
| SCHEMBL639291 | 0.82 | GABRG2 (0.74) | GABRG2GABRB3GABRA3GABRA2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1925614-A1 | Anxiolytic agents with reduced sedative and ataxic effects | Wisys Technology Foundation, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |