Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 9/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839569 | 0.85 | BRPF1 (0.54) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1838548 | 0.81 | BRPF1 (0.55) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1839524 | 0.81 | BRPF1 (0.51) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1839961 | 0.81 | BRPF1 (0.51) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1841666 | 0.81 | BRPF1 (0.51) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL2008903 | 0.81 | BRPF1 (0.51) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1843146 | 0.81 | BRPF1 (0.54) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL14217731 | 0.80 | BRPF1 (0.56) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1844278 | 0.80 | BRPF1 (0.54) | BRPF1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL1842642 | 0.80 | BRPF1 (0.54) | BRPF1RAB9AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059370-A2 | SUBSTITUTED BICYCLOCARBOXYAMIDE COMPOUNDS | PFIZER JAPAN INC. (JP) | 2008-05-22 | — | — | WO | disclosed |